2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. MC-Val-Cit-PAB-NH-C2-NH-Boc

MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

MC-Val-Cit-PAB-NH-C2-NH-Boc Chemical Structure

MC-Val-Cit-PAB-NH-C2-NH-Boc Chemical Structure

CAS No. : 1616727-22-0

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Based on 1 publication(s) in Google Scholar

MC-Val-Cit-PAB-NH-C2-NH-Boc Related Antibodies

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Description

MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Protease Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MC-Val-Cit-PAB-NH-C2-NH-Boc Related Antibodies
Molecular Weight

758.86

Formula

C36H54N8O10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)(C)OC(NCCNC(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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MC-Val-Cit-PAB-NH-C2-NH-Boc Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-Val-Cit-PAB-NH-C2-NH-Boc1616727-22-0ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
MC-Val-Cit-PAB-NH-C2-NH-Boc
Cat. No.:
HY-132973
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