2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. MC-VC-PABC-C6-alpha-Amanitin

MC-VC-PABC-C6-alpha-Amanitin is an antibody agent conjugate consisting of an anticancer toxin alpha-Amanitin (HY-19610) and a monoclonal antibody MC-VC-PABC-C6. Among them, alpha-Amanitin is a potent inhibitor of RNA polymerase IIα. MC-VC-PABC-C6-alpha-Amanitin accurately targets HER2 receptors, specifically recognizes HER2-positive tumor cells. It is widely used in breast cancer and gastric cancer research.

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MC-VC-PABC-C6-alpha-Amanitin Chemical Structure

MC-VC-PABC-C6-alpha-Amanitin Chemical Structure

CAS No. : 2922514-69-8

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MC-VC-PABC-C6-alpha-Amanitin Related Antibodies

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Description

MC-VC-PABC-C6-alpha-Amanitin is an antibody agent conjugate consisting of an anticancer toxin alpha-Amanitin (HY-19610) and a monoclonal antibody MC-VC-PABC-C6. Among them, alpha-Amanitin is a potent inhibitor of RNA polymerase IIα. MC-VC-PABC-C6-alpha-Amanitin accurately targets HER2 receptors, specifically recognizes HER2-positive tumor cells. It is widely used in breast cancer and gastric cancer research[1].

IC50 & Target

Daunorubicins/Doxorubicins

 

Molecular Weight

1616.79

Formula

C74H105N17O22S
CAS No.
SMILES

O=S(C[C@@](NC(CNC([C@@]([C@@H](C)CC)([H])N1)=O)=O)([H])C(N[C@@](C(N(C[C@H](O)C2)[C@]2([H])C3=O)=O)([H])CC(N)=O)=O)C4=C(C[C@](C(NCC1=O)=O)([H])NC([C@](N3)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)C=C6)=O)C=C5N4
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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MC-VC-PABC-C6-alpha-Amanitin Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-VC-PABC-C6-alpha-Amanitin2922514-69-8Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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