1. Metabolic Enzyme/Protease Neuronal Signaling NF-κB Immunology/Inflammation
  2. NADPH Oxidase Monoamine Oxidase Reactive Oxygen Species NO Synthase Interleukin Related
  3. MC4762

MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. MC4762 has anti-inflammatory activity, can inhibit the production of ROS, and downregulate the expression of pro-inflammatory cytokines iNOS, IL-1β, and IL-6.

For research use only. We do not sell to patients.

MC4762 Chemical Structure

MC4762 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All NADPH Oxidase Isoform Specific Products:

View All Monoamine Oxidase Isoform Specific Products:

View All NO Synthase Isoform Specific Products:

View All Interleukin Related Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. MC4762 has anti-inflammatory activity, can inhibit the production of ROS, and downregulate the expression of pro-inflammatory cytokines iNOS, IL-1β, and IL-6[1].

IC50 & Target[1]

MAO-B

0.182 μM (IC50)

NOX2

0.155 μM (IC50)

Molecular Weight

441.51

Formula

C23H19N7OS

SMILES

C#CCN(CC1=CC=C(CN2N=NC3=C(SC4=NC5=CC=CC=C5O4)N=CN=C32)C=C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
MC4762
Cat. No.:
HY-172451
Quantity:
MCE Japan Authorized Agent: