2. Academic Validation
  3. Isolation of ekatetrone, a new metabolite of producing variants of Streptomyces aureofaciens

Isolation of ekatetrone, a new metabolite of producing variants of Streptomyces aureofaciens

  • J Antibiot (Tokyo). 1978 Sep;31(9):850-4. doi: 10.7164/antibiotics.31.850.
M Podojil,  Z Vanĕk,  V Prikrylová,  M Blumauerová
PMID: 101501 DOI: 10.7164/antibiotics.31.850
Abstract

From a mixture of substances formed by producing strains of Streptomyces aureofaciens under conditions of submerged fermentation a new metabolite, ekatetrone, was isolated. Its isolation and basic physical and chemical data are described. Ekatetrone is a quinone derivative with a carboxamide group. In tests in vitro with cells of Ehrlich's ascites tumour evidence was provided that ekatetrone inhibits proteo- and nucleosynthesis.

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