2. Academic Validation
  3. Orizabins V-VIII, tetrasaccharide glycolipids from the Mexican scammony root (Ipomoea orizabensis)

Orizabins V-VIII, tetrasaccharide glycolipids from the Mexican scammony root (Ipomoea orizabensis)

  • J Nat Prod. 1999 Aug;62(8):1096-100. doi: 10.1021/np9900627.
B Hernández-Carlos 1,  R Bye,  R Pereda-Miranda
Affiliations

Affiliation

  • 1 Departamento de Farmacia, Facultad de Química, and Jardín Botánico, Instituto de Biología, Universidad Nacional Autónoma de México, Coyoacán 04510, D.F., México.
PMID: 10479311 DOI: 10.1021/np9900627
Abstract

An extensive investigation of the so-called jalapin resinoid obtained from roots of the Mexican scammony, Ipomoea orizabensis, using high field NMR spectroscopy led to the characterization of six glycosides, including the known scammonins I (1) and II (2) and four new tetrasaccharides of jalapinolic acid, orizabins V-VIII (3-6). All the isolates (1-6) were found to be weakly cytotoxic toward human oral epidermoid carcinoma (KB).

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