2. Academic Validation
  3. Septo-optic dysplasia plus: a spectrum of malformations of cortical development

Septo-optic dysplasia plus: a spectrum of malformations of cortical development

  • Neurology. 2000 Apr 25;54(8):1701-3. doi: 10.1212/wnl.54.8.1701.
S P Miller 1,  M I Shevell,  Y Patenaude,  C Poulin,  A M O'Gorman
Affiliations

Affiliation

  • 1 Departments of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada.
PMID: 10762523 DOI: 10.1212/wnl.54.8.1701
Abstract

The authors describe three children with septo-optic dysplasia (SOD)-plus: SOD and an associated malformation of cortical development. All three children had developmental delay, and two of the children had significant associated motor deficits. The associated cortical malformations with SOD include a spectrum of disorders of neuronal organization, not limited, as previously described, to schizencephaly. SOD-plus should be suspected in children with SOD and developmental delay.

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