2. Academic Validation
  3. Detection and quantification of CD4(+) T cells with specificity for a new major histocompatibility complex class II-restricted influenza A virus matrix protein epitope in peripheral blood of influenza patients

Detection and quantification of CD4(+) T cells with specificity for a new major histocompatibility complex class II-restricted influenza A virus matrix protein epitope in peripheral blood of influenza patients

  • J Virol. 2000 Sep;74(18):8740-3. doi: 10.1128/jvi.74.18.8740-8743.2000.
T Linnemann 1,  G Jung,  P Walden
Affiliations

Affiliation

  • 1 Department of Dermatology and Allergy, Charité, Medical School of the Humboldt University, D-10089 Berlin, Germany.
PMID: 10954576 DOI: 10.1128/jvi.74.18.8740-8743.2000
Abstract

FVFTLTVPS was identified as the core sequence of a new major histocompatibility complex class II-restricted T-cell epitope of Influenza Virus matrix protein. Epitope-specific CD4(+) T cells were detected in the peripheral blood of patients with frequencies of up to 0.94%, depending on the number of additional terminal Amino acids.

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