2. Academic Validation
  3. Glomosporin, a novel antifungal cyclic depsipeptide from Glomospora sp. I. Production, isolation, physico-chemical properties and biological activities

Glomosporin, a novel antifungal cyclic depsipeptide from Glomospora sp. I. Production, isolation, physico-chemical properties and biological activities

  • J Antibiot (Tokyo). 2000 Jun;53(6):597-602. doi: 10.7164/antibiotics.53.597.
T Sato 1,  D Ishiyama,  R Honda,  H Senda,  H Konno,  S Tokumasu,  S Kanazawa
Affiliations

Affiliation

  • 1 Institute of Biotechnology Applied to Soil Eumycetes, Akita, Japan.
PMID: 10966075 DOI: 10.7164/antibiotics.53.597
Abstract

A novel Antifungal cyclic depsipeptide termed glomosporin, which has a fatty acyl side chain, was isolated from a barley solid culture of Glomospora sp. The strain was isolated from fallen pine leaves collected in Fukusima Prefecture, Japan and identified as Glomospora sp. BAUA 2825. Glomosporin was purified by butanol extraction followed by preparative HPLC. Glomosporin showed antimicrobial activity against fungi including clinically important Aspergillus fumigatus.

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