2. Academic Validation
  3. Optically active N-acetyldopamine dimer of the crude drug "Zentai," the cast-off shell of the Cicada, Cryptotympana sp

Optically active N-acetyldopamine dimer of the crude drug "Zentai," the cast-off shell of the Cicada, Cryptotympana sp

  • Chem Pharm Bull (Tokyo). 2000 Nov;48(11):1749-52. doi: 10.1248/cpb.48.1749.
N Noda 1,  S Kubota,  Y Miyata,  K Miyahara
Affiliations

Affiliation

  • 1 Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan. noda@pharm.setsunan.ac.jp
PMID: 11086906 DOI: 10.1248/cpb.48.1749
Abstract

Two optically active N-acetyldopamine dimers together with four phenolic monomers were isolated from the crude drug "Zentai," a cast-off shell of the cicada of Cryptotympana sp. (Cicadidae). The former two were 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivatives carrying substituents at the 3 and 6 (or 7) positions, which are known to be components of sclerotized insect cuticles. Their structures including absolute configurations were determined on the basis of NMR and circular dichroism (CD) spectroscopic data.

Figures
Products