2. Academic Validation
  3. Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae

Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae

  • J Nat Prod. 2001 Jan;64(1):88-91. doi: 10.1021/np0003084.
M Kuroda 1,  Y Mimaki,  A Yokosuka,  Y Sashida,  J A Beutler
Affiliations

Affiliation

  • 1 Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1, Horinouchi, Hachioji, Tokyo 192-0392, Japan.
PMID: 11170674 DOI: 10.1021/np0003084
Abstract

Further phytochemical analysis of the bulbs of Ornithogalum saundersiae has yielded two new cytotoxic cholestane triglycosides (1 and 2). The structures of these compounds were determined by spectroscopic analysis, including 2D NMR spectroscopic data, and the results of hydrolytic cleavage. Compounds 1 and 2 and several analogues were evaluated for their cytotoxicity against HL-60 cells.

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