2. Academic Validation
  3. New bioactive sulfated metabolites from the Mediterranean tunicate Sidnyum turbinatum

New bioactive sulfated metabolites from the Mediterranean tunicate Sidnyum turbinatum

  • J Nat Prod. 2001 Feb;64(2):219-21. doi: 10.1021/np000438c.
A Aiello 1,  S Carbonelli,  E Fattorusso,  T Iuvone,  M Menna
Affiliations

Affiliation

  • 1 Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Via D. Montesano 49, I-80131, Napoli, Italy.
PMID: 11430005 DOI: 10.1021/np000438c
Abstract

In addition to the known sodium 3,7,11,15-tetramethylhexadeca-1,19-diyl sulfate (4), the BuOH extract of the Mediterranean tunicate Sidnyum turbinatum was shown to contain four new metabolites: 1-heptadecanyl sulfate (1), 1-octadecanyl sulfate (2), sodium (2S)-2,6,10,14-tetramethylpentadeca-1,18-diyl sulfate (3), and 1-hexyl sulfate (5). Their structures were determined by spectroscopic and chemical methods. Compounds 1-5 exhibited in vitro antiproliferative activity estimated on the WEHI 164 cell line.

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