2. Academic Validation
  3. Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis

Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis

  • Pharmazie. 2001 Aug;56(8):657-60.
M Ahmed 1,  H A Shikha,  S K Sadhu,  M T Rahman,  B K Datta
Affiliations

Affiliation

  • 1 Department of Pharmacy, University of Dhaka, Dhaka, Bangladesh. mua@du.bangla.net
PMID: 11534346
Abstract

Scoparinol, a diterpene, isolated from Scoparia dulcis showed significant analgesic (p < 0.001) and anti-inflammatory activity (p < 0.01) in Animals. A sedative action of scoparinol was demonstrated by a marked potentiation of pentobarbital-induced sedation with a significant effect on both onset and duration of sleep (p < 0.05). Measurement of urine volume after administration of scoparinol indicated its significant diuretic action.

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