2. Academic Validation
  3. New saponins from the starfish Certonardoa semiregularis

New saponins from the starfish Certonardoa semiregularis

  • J Nat Prod. 2002 Nov;65(11):1649-56. doi: 10.1021/np020234r.
Weihong Wang 1,  Famei Li,  Naseer Alam,  Yonghong Liu,  Jongki Hong,  Chong-Kyo Lee,  Kwang Sik Im,  Jee H Jung
Affiliations

Affiliation

  • 1 College of Pharmacy, Pusan National University, Busan 609-735, Korea.
PMID: 12444692 DOI: 10.1021/np020234r
Abstract

Ten new saponins designated as certonardosides A-J (1-5, 7-11) and the known halityloside D (6) were isolated from the brine shrimp active fraction of the MeOH extract of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical manipulation. The compounds were evaluated for Antiviral activity against HIV, HSV, CoxB, EMCV, and VSV and displayed insignificant activity within the range of noncytotoxic concentrations.

Figures