2. Academic Validation
  3. Recent advances in understanding chromatin remodeling by Swi/Snf complexes

Recent advances in understanding chromatin remodeling by Swi/Snf complexes

  • Curr Opin Genet Dev. 2003 Apr;13(2):136-42. doi: 10.1016/s0959-437x(03)00022-4.
Joseph A Martens 1,  Fred Winston
Affiliations

Affiliation

  • 1 Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.
PMID: 12672490 DOI: 10.1016/s0959-437x(03)00022-4
Abstract

Members of the Swi/Snf family of chromatin-remodeling complexes play critical roles in transcriptional control. Recent studies have made significant advances in our understanding of the fundamental aspects of Swi/Snf complexes, including the roles of specific subunits, the repression of transcription, and the mechanism of remodeling. In addition, new findings also indicate an important role for the Swi/Snf-related complex, RSC, in controlling gene expression.

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