2. Academic Validation
  3. Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis

Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis

  • Kisaengchunghak Chapchi. 1976 Dec;14(2):140-146. doi: 10.3347/kjp.1976.14.2.140.
Han Jong Rim 1,  Myung Se Kim,  Joung Hwan Ha,  Dong Shik Chang
Affiliations

Affiliation

  • 1 Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University, Seoul, Korea.
PMID: 12913443 DOI: 10.3347/kjp.1976.14.2.140
Abstract

The new drug niclofolan (bayer 9015, Bilevon), 5,5'-dichloro-2,2'-dihydroxy-3, 3'-dinitrobiphenyl, has been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.

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