1. Academic Validation
  2. Chandrananimycins A approximately C: production of novel anticancer antibiotics from a marine Actinomadura sp. isolate M048 by variation of medium composition and growth conditions

Chandrananimycins A approximately C: production of novel anticancer antibiotics from a marine Actinomadura sp. isolate M048 by variation of medium composition and growth conditions

  • J Antibiot (Tokyo). 2003 Jul;56(7):622-9. doi: 10.7164/antibiotics.56.622.
Rajendra P Maskey 1 Fuchao Li Song Qin Heinz H Fiebig Hartmut Laatsch
Affiliations

Affiliation

  • 1 Department of Organic Chemistry, University of Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany.
Abstract

In our screening of marine actinomycetes for bioactive principles, three novel Antibiotics designated as chandrananimycin A (3c), B (3d) and C (4) were isolated from the culture broth of a marine Actinomadura sp. isolate M045. The structures of the new Antibiotics were determined by detailed interpretation of mass, 1D and 2D NMR spectra.

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