2. Academic Validation
  3. beta-alanine dipeptides as MC4R agonists

beta-alanine dipeptides as MC4R agonists

  • Bioorg Med Chem Lett. 2003 Dec 15;13(24):4341-4. doi: 10.1016/j.bmcl.2003.09.036.
Réjean Ruel 1,  Timothy F Herpin,  Lawrence Iben,  Guanglin Luo,  Alain Martel,  Helen Mason,  Gail Mattson,  Brigitte Poirier,  Edward H Ruediger,  Dan Shi,  Carl Thibault,  Guixue Yu,  Ildiko Antal Zimanyi,  Graham S Poindexter,  John E Macor
Affiliations

Affiliation

  • 1 Bristol-Myers Squibb Pharmaceutical Research Institute, 100 boul. de l'Industrie, Candiac, Quebec, Canada J5R 1J1. rejean.ruel@bms.com
PMID: 14643322 DOI: 10.1016/j.bmcl.2003.09.036
Abstract

beta-Alanine derivative 2 (IC(50)=16 nM) and related compounds were found to be potent MC4R agonists.

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