1. Academic Validation
  2. Saponins from the flower buds of Buddleja officinalis

Saponins from the flower buds of Buddleja officinalis

  • J Nat Prod. 2004 Jan;67(1):10-3. doi: 10.1021/np0300131.
Hongzhu Guo 1 Kazuo Koike Wei Li Tadaaki Satou Dean Guo Tamotsu Nikaido
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
Abstract

Five new saponins, mimengosides C-G (1-5), were isolated from the flower buds of Buddleja officinalis along with five known compounds, namely, songaroside A, acteoside, phenylethyl 2-glucoside, echinacoside, and phenylethyl alcohol 8-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside. The structures of 1-5 were elucidated using spectroscopic and chemical methods, and these compounds were evaluated for their inhibitory effects against HL-60 leukemia cells.

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