1. Academic Validation
  2. Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line

Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line

  • J Nat Prod. 2004 Jan;67(1):46-8. doi: 10.1021/np030293k.
Norio Nakamura 1 Akiko Hirakawa Jiang-Jing Gao Hiroko Kakuda Motoo Shiro Yasuhiro Komatsu Chia-chin Sheu Masao Hattori
Affiliations

Affiliation

  • 1 Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
Abstract

Five new maleic and succinic acid derivatives were isolated from the mycelium of Antrodia camphorata. Their structures were determined by various spectroscopic means. Maleimide derivatives 2 and 3 showed appreciable cytotoxic activity against LLC cells.

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