1. Academic Validation
  2. Four new triterpenoids from Maytenus ilicifolia

Four new triterpenoids from Maytenus ilicifolia

  • J Nat Prod. 2004 Mar;67(3):469-71. doi: 10.1021/np030379d.
Ayumi Ohsaki 1 Yoji Imai Meiko Naruse Shin-Ichi Ayabe Kanki Komiyama Junko Takashima
Affiliations

Affiliation

  • 1 Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda-ku, Tokyo 101-0062, Japan. a-ohsaki.fm@tmd.ac.jp
Abstract

Four new triterpenoids with various skeletons, maytefolins A-C (1-3) and uvaol-3-caffeate (4), were isolated from the leaves of a Brazilian medicinal plant, Maytenus ilicifolia, together with five known triterpenoids. Of these triterpenoids only erythrodiol exhibited significant cytotoxicity against KB/S, KB/VJ300, and KU 19-20 cells.

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