2. Academic Validation
  3. New quassinoids, javanicolides C and D and javanicosides B--F, from seeds of Brucea javanica

New quassinoids, javanicolides C and D and javanicosides B--F, from seeds of Brucea javanica

  • J Nat Prod. 2004 May;67(5):863-8. doi: 10.1021/np030484n.
Ik Hwi Kim 1,  Satoru Takashima,  Yukio Hitotsuyanagi,  Tomoyo Hasuda,  Koichi Takeya
Affiliations

Affiliation

  • 1 School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
PMID: 15165151 DOI: 10.1021/np030484n
Abstract

Two new quassinoids, javanicolides C and D, and five new quassinoid glucosides, javanicosides B-F, were isolated from the seeds of Brucea javanica, along with eight known quassinoids, i.e., yadanziolides A, C, D, and S, bruceins D and E, brusatol, and the aglycone of yadanzioside D, and 19 known quassinoid glucosides, i.e., yadanziosides A-G, I, and K-P, bruceosides A-C and E, and bruceantinoside A. Their structures were elucidated by analysis of spectroscopic data and chemical evidence.

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