2. Academic Validation
  3. Bioactive constituents from Boswellia papyrifera

Bioactive constituents from Boswellia papyrifera

  • J Nat Prod. 2005 Feb;68(2):189-93. doi: 10.1021/np040142x.
Atta-ur-Rahman 1,  Humera Naz,  Fadimatou,  Talat Makhmoor,  Amsha Yasin,  Naheed Fatima,  F N Ngounou,  S F Kimbu,  B L Sondengam,  M Iqbal Choudhary
Affiliations

Affiliation

  • 1 H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan.
PMID: 15730241 DOI: 10.1021/np040142x
Abstract

Phytochemical investigation of the stem bark extract of Boswellia papyrifera afforded two new stilbene glycosides, trans-4',5-dihydroxy-3-methoxystilbene-5-O-{alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (1), trans-4',5-dihydroxy-3-methoxystilbene-5-O-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (2), and a new triterpene, 3alpha-acetoxy-27-hydroxylup-20(29)-en-24-oic acid (3), along with five known compounds, 11-keto-beta-boswellic acid (4), beta-elemonic acid (7), 3alpha-acetoxy-11-keto-beta-boswellic acid (8), beta-boswellic acid (9), and beta-sitosterol (10). The stilbene glycosides exhibited significant inhibition of phosphodiesterase I and Xanthine Oxidase. The Triterpenes (3-9) exhibited prolyl endopeptidase inhibitory activities.

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