2. Academic Validation
  3. Antibacterial caged-tetraprenylated xanthones from the fruits of Garcinia hanburyi

Antibacterial caged-tetraprenylated xanthones from the fruits of Garcinia hanburyi

  • Chem Pharm Bull (Tokyo). 2005 Jul;53(7):850-2. doi: 10.1248/cpb.53.850.
Yaowapa Sukpondma 1,  Vatcharin Rukachaisirikul,  Souwalak Phongpaichit
Affiliations

Affiliation

  • 1 Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
PMID: 15997152 DOI: 10.1248/cpb.53.850
Abstract

A new caged-tetraprenylated xanthone, hanburinone (1), was isolated from the fresh fruits of Garcinia hanburyi together with four known caged-tetraprenylated xanthones; isomoreollin B (2), morellin (3), moreollic acid (4) and morellic acid (5). Their structures were elucidated by analysis of spectroscopic data and comparison of the NMR data with those reported previously. Compounds 4 and 5 showed moderately Antibacterial activity against methicillin-resistant Staphylococcus aureus with a MIC value of 25 microg/ml.

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