2. Academic Validation
  3. New natural urease inhibitors from Ranunculus repens

New natural urease inhibitors from Ranunculus repens

  • J Enzyme Inhib Med Chem. 2006 Feb;21(1):17-9. doi: 10.1080/14756360500319210.
Wahib Noor Khan 1,  Muhammad Arif Lodhi,  Irshad Ali,  Azhar-Ul-Haq,  Abdul Malik,  Salma Bilal,  Rukhsana Gul,  Muhammad Iqbal Choudhary
Affiliations

Affiliation

  • 1 Department of Chemistry, Gomal University, D I Khan, Pakistan.
PMID: 16570500 DOI: 10.1080/14756360500319210
Abstract

Phytochemical investigations on the chloroform and ethyl acetate soluble fractions of the roots of Ranunculus repens led to the isolation of methyl 3,4,5-trihydroxybenzoate 1, R(+)- 4-methoxydalbergione 2 and R(+)-dalbergiophenol 3. The structures of these compounds were established through spectral studies including 1D and 2D NMR experiments and by comparison with literature data. These compounds showed potent inhibitory activity against urease.

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