2. Academic Validation
  3. Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424

Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424

  • J Nat Prod. 2006 Jun;69(6):980-2. doi: 10.1021/np060164e.
Vatcharin Rukachaisirikul 1,  Sirinya Chantaruk,  Wipapan Pongcharoen,  Masahiko Isaka,  Sanisa Lapanun
Affiliations

Affiliation

  • 1 Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand. vatcharin.r@psu.ac.th
PMID: 16792425 DOI: 10.1021/np060164e
Abstract

Five new chromones, named lachnones A-E (1-5), were isolated from the filamentous fungus Lachnum sp. BCC 2424 along with known (2E,6S)-2,6-dimethyl-2,7-octadiene-1,6-diol. Their structures were elucidated by spectroscopic methods. Lachnones B (2) and D (4) mildly inhibited the growth of Mycobacterium tuberculosis, both with MIC values of 200 microg/mL.

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