2. Academic Validation
  3. Phenolic constituents of the roots of Sophora flavescens

Phenolic constituents of the roots of Sophora flavescens

  • J Nat Prod. 2006 Aug;69(8):1237-40. doi: 10.1021/np060189d.
Chien-Chang Shen 1,  Ting-Wei Lin,  Yu-Ling Huang,  Shr-Ting Wan,  Bor-Jinn Shien,  Chien-Chih Chen
Affiliations

Affiliation

  • 1 National Research Institute of Chinese Medicine, No. 155-1, Sec. 2, Li Nung Street, Peitou, Taipei, Taiwan, Republic of China.
PMID: 16933887 DOI: 10.1021/np060189d
Abstract

From the roots of Sophora flavescens collected in Taiwan, four new prenylflavonoids, sophoraflavanone K (1), sophoraflavanone L (2), 8-lavandulylkaempferol (3), and cyclokuraridin (4), a new arylbenzofuran, 2-(2,4-dihydroxy-5-prenylphenyl)-5,6-methylenedioxybenzofuran (5), and a new prenyldibenzoyl derivative, sophoradione (6), were isolated. The structures of 1-6 were determined by spectroscopic data analysis. Compounds 2-6 were evaluated for cytotoxic activity against the KB epidermoid carcinoma cell line.

Figures
Products