2. Academic Validation
  3. Malvone A, a phytoalexin found in Malva sylvestris (family Malvaceae)

Malvone A, a phytoalexin found in Malva sylvestris (family Malvaceae)

  • Phytochemistry. 2006 Nov;67(21):2376-9. doi: 10.1016/j.phytochem.2006.08.010.
Olga Veshkurova 1,  Zamira Golubenko,  Egor Pshenichnov,  Irina Arzanova,  Vyacheslav Uzbekov,  Elvira Sultanova,  Shavkat Salikhov,  Howard J Williams,  Joseph H Reibenspies,  Lorraine S Puckhaber,  Robert D Stipanovic
Affiliations

Affiliation

  • 1 A.S. Sadykov Institute of Bioorganic Chemistry, Academy of Science Uzbekistan, Tashkent, Uzbekistan.
PMID: 16996095 DOI: 10.1016/j.phytochem.2006.08.010
Abstract

The isolation and structure of a phytoalexin, malvone A (2-methyl-3-methoxy-5,6-dihydroxy-1,4-naphthoquinone) is reported. Malvone A formation is induced in Malva sylvestris L. by the plant pathogen Verticillium dahliae. In a turbimetric assay for toxicity to V. dahliae, it had an ED50 value of 24 microg/ml. The structure of malvone A was determined by MS and NMR spectroscopy, and by X-ray crystallographic analysis. The X-ray analysis showed water molecules were located in channels that run along the a-axis.

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