Superficial siderosis: a case report and review of the literature

Nat Clin Pract Neurol. 2007 Jan;3(1):54-8; quiz 59. doi: 10.1038/ncpneuro0356.

Michael Levy ¹, Christine Turtzo, Rafael H Llinas

Affiliations

Affiliation

1 Johns Hopkins Hospital, Baltimore, MD, USA. mlevy@jhmi.edu

PMID: 17205075 DOI: 10.1038/ncpneuro0356

Abstract

Background: A 48-year-old man with a past history of a car-accident-induced coma at the age of 3 years and spontaneous bilateral subdural hematomas at the age of 34 years presented with a 2-year history of worsening gait difficulties, clumsiness and dysarthria. CT scans of the brain taken during the 6 months leading up to his presentation had revealed chronic subarachnoid hemorrhage, but angiograms had not been able to identify the source of bleeding.

Investigations: Neurological examination, brain MRI scan, lumbar puncture, four-vessel cerebral angiogram and spinal angiogram.

Diagnosis: Superficial siderosis; a complete review of the current literature on the condition is provided.

Management: Iron chelating agents.

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