2. Academic Validation
  3. [Biological activity tests of chemical constituents from two Brazilian Labiatae plants]

[Biological activity tests of chemical constituents from two Brazilian Labiatae plants]

  • Yakugaku Zasshi. 2007 Feb;127(2):389-95. doi: 10.1248/yakushi.127.389.
Takahiko Isobe 1,  Matsumi Doe,  Yoshiki Morimoto,  Kumiko Nagata,  Noriyoshi Masuoka,  Ayumi Ohsaki
Affiliations

Affiliation

  • 1 Department of Chemistry, Hyogo College of Medicine, Nishinomiya City, Japan. isobetkh@hyo-med.ac.jp
PMID: 17268160 DOI: 10.1248/yakushi.127.389
Abstract

We studied the bioactivities of constituents from two tropical medicinal Plants, Cunila spicata and Hyptis fasciculata. These Plants found in Brazil belong to the Labiatae family. Four known compounds obtained from these herbs were identified as 3alpha, 24-dihydoxylurs-12-en-28-oic acid, betulinic acid, aurantiamide acetate, and aurantiamide benzoate by spectroscopic means. 3alpha, 24-Dihydoxylurs-12-en-28-oic acid has potent inhibitory activity against Streptococcus salivarius, Streptococcus pneumoniae, Streptococcus pyogenes, and Porphyromomas gingivalis. Aurantiamide benzoate exhibited moderate inhibitory activity against Xanthine Oxidase. It was clarified that herbs Cunila spicata and Hyptis fasciculata are effective against bronchitis and gout.

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