2. Academic Validation
  3. Novel cytotoxic principles of Formosan Ganoderma lucidum

Novel cytotoxic principles of Formosan Ganoderma lucidum

  • J Nat Prod. 1991 Jul-Aug;54(4):998-1002. doi: 10.1021/np50076a012.
C N Lin 1,  W P Tome,  S J Won
Affiliations

Affiliation

  • 1 Natural Products Research Center, Kaohsiung Medical College, Taiwan, Republic of China.
PMID: 1791484 DOI: 10.1021/np50076a012
Abstract

Two new steryl esters, ergosta-7,22-dien-3 beta-yl linoleate [1] and 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-yl linoleate [3], and a novel steroid, ergosta-7,22-diene- 3 beta,3 alpha,9 alpha-triol [5], have been isolated from the fruiting bodies of Formosan Ganoderma lucidum and characterized. A new lanostanoid, 3 beta-hydroxy-26-oxo-5 alpha-lanosta- 8,24-dien-11-one, and the new steroid exhibited potent inhibition of KB cells and human PLC/PRF/5 cells in vitro.

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