1. Academic Validation
  2. Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii

Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii

  • J Nat Prod. 2007 Oct;70(10):1565-9. doi: 10.1021/np0702133.
Martin Senn 1 Sigmund Gunzenhauser Reto Brun Urs Séquin
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland.
Abstract

From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1- 4, were isolated, three of which ( 1- 3) were active against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Plasmodium falciparum, and Leishmania donovani.

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