2. Academic Validation
  3. Securinega alkaloids from the wood of Securinega suffruticosa var. amamiensis

Securinega alkaloids from the wood of Securinega suffruticosa var. amamiensis

  • J Nat Prod. 2007 Dec;70(12):2003-5. doi: 10.1021/np0780102.
Ayumi Ohsaki 1,  Yukino Kobayashi,  Kaisuke Yoneda,  Akio Kishida,  Haruaki Ishiyama
Affiliations

Affiliation

  • 1 Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan. a-ohsaki.fm@tmd.ac.jp
PMID: 18052029 DOI: 10.1021/np0780102
Abstract

Three new Securinega Alkaloids, secu'amamines B-D ( 1- 3), were isolated from the wood of the Japanese medicinal plant Securinega suffruticosa var. amamiensis, together with five known analogues ( 4, 6- 9). The structures 1- 3 were elucidated by spectroscopic methods including 2D NMR, and all eight compounds were evaluated for cytotoxicity against two Cancer cell lines.

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