2. Natural Products
  3. Plants Alkaloids
  4. Euphorbiaceae Pyridine Alkaloids
  5. Flueggea suffruticosa (Pall.) Baill.
  6. Securitinine

Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var.

For research use only. We do not sell to patients.

Securitinine Chemical Structure

Securitinine Chemical Structure

CAS No. : 13861-71-7

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Based on 1 publication(s) in Google Scholar

Securitinine Related Antibodies

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Description

Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 11
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
[PMID: 31082231]
BV-2 IC50
31.5 μM
Compound: 11
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay
[PMID: 31082231]
HCT-15 IC50
> 10 μM
Compound: 11
Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay
Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay
[PMID: 31082231]
SK-MEL-2 IC50
> 10 μM
Compound: 11
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay
Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay
[PMID: 31082231]
SK-OV-3 IC50
> 10 μM
Compound: 11
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay
[PMID: 31082231]
Molecular Weight

247.29

Formula

C14H17NO3
CAS No.
SMILES

O=C(O1)C=C2[C@@]13[C@@](C[C@@H](OC)CC4)([H])N4[C@](C3)([H])C=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Securitinine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Securitinine13861-71-7OthersSecurinega alkaloidSecurinega suffruticosa varInhibitorinhibitorinhibit

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HY-N7359
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