2. Academic Validation
  3. Terpenoids from Toona ciliata

Terpenoids from Toona ciliata

  • J Nat Prod. 2009 Apr;72(4):685-9. doi: 10.1021/np800811b.
Hua-Dong Chen 1,  Sheng-Ping Yang,  Yan Wu,  Lei Dong,  Jian-Min Yue
Affiliations

Affiliation

  • 1 State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Zhangjiang Hi-Tech Park, Shanghai, People's Republic of China.
PMID: 19275174 DOI: 10.1021/np800811b
Abstract

Three new norlimonoids (1-3), two new tirucallane-type triterpenoids (4 and 5), and a new pimaradiene-type diterpenoid (6), along with two known limonoids and eight known tirucallane-type triterpenoids, were isolated from the leaves and twigs of Toona ciliata. Their structures were elucidated on the basis of spectroscopic data. Toonaciliatin M (6) showed moderate Antifungal activity against Trichophyton rubrum with an MIC of 12.5 microg/mL.

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