1. Academic Validation
  2. 2-Arylbenzofuran Derivatives from Morus cathayana

2-Arylbenzofuran Derivatives from Morus cathayana

  • J Nat Prod. 2009 May 22;72(5):966-8. doi: 10.1021/np800789y.
Gang Ni 1 Qing-Jian Zhang Zhong-Fei Zheng Ruo-Yun Chen De-Quan Yu
Affiliations

Affiliation

  • 1 The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, People's Republic of China.
Abstract

Four new 2-arylbenzofuran derivatives, cathafurans A (1), B (2), C (3), and D (4), were isolated from the stem bark of Morus cathayana. Their structures were determined by spectroscopic methods. Compounds 2 and 3 exhibited moderate activities against five human Cancer cell lines, with IC(50) values ranging from 6.17 to 9.60 microg/mL.

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