2. Academic Validation
  3. Anthracycline metabolites from Streptomyces violaceus A262. II. New anthracycline epelmycins produced by a blocked mutant strain SU2-730

Anthracycline metabolites from Streptomyces violaceus A262. II. New anthracycline epelmycins produced by a blocked mutant strain SU2-730

  • J Antibiot (Tokyo). 1991 Oct;44(10):1121-9. doi: 10.7164/antibiotics.44.1121.
O Johdo 1,  Y Watanabe,  T Ishikura,  A Yoshimoto,  H Naganawa,  T Sawa,  T Takeuchi
Affiliations

Affiliation

  • 1 Central Research Laboratories, Mercian Corporation, Fujisawa, Japan.
PMID: 1955395 DOI: 10.7164/antibiotics.44.1121
Abstract

New anthracycline Antibiotics, identified as epsilon-rhodomycinone glycosides, were isolated from the culture broth of a blocked mutant of beta-rhodomycin-producing Streptomyces violaceus A262. They were designated as epelmycins A, B, C, D and E, and assayed for their in vitro cytotoxicities against murine leukemic L1210 Cell Culture and the antimicrobial activities in comparison with known anthracycline Antibiotics.

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