2. Academic Validation
  3. Cytotoxic triterpenoids from the rhizomes of Astilbe chinensis

Cytotoxic triterpenoids from the rhizomes of Astilbe chinensis

  • J Nat Prod. 2009 Jul;72(7):1241-4. doi: 10.1021/np900028v.
Xing-Fu Cai 1,  Bo-Young Park,  Kyung-Seop Ahn,  Ok-Kyoung Kwon,  Hyeong-Kyu Lee,  Sei-Ryang Oh
Affiliations

Affiliation

  • 1 Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea.
PMID: 19585998 DOI: 10.1021/np900028v
Abstract

Six new triterpenoids (1-6) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 1-6 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human Cancer lines.

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