2. Academic Validation
  3. Isolation, structure, and synthesis of novel 4-quinolinone alkaloids from Esenbeckia leiocarpa

Isolation, structure, and synthesis of novel 4-quinolinone alkaloids from Esenbeckia leiocarpa

  • J Nat Prod. 1990 Nov-Dec;53(6):1508-13. doi: 10.1021/np50072a017.
T Nakatsu 1,  T Johns,  I Kubo,  K Milton,  M Sakai,  K Chatani,  K Saito,  Y Yamagiwa,  T Kamikawa
Affiliations

Affiliation

  • 1 Division of Entomology and Parasitology, College of Natural Resources, Berkeley, California.
PMID: 1965201 DOI: 10.1021/np50072a017
Abstract

Two new biocidal quinolinone Alkaloids, 3-methoxy-1-methyl-2-propyl-4-quinolone [1] and 2(1'-ethylpropyl)-1-methyl-4-quinolone [2], were efficiently isolated using reversed-phase recycling hplc from the leaves of Esenbeckia leiocarpa. The structures were determined through spectroscopic data and confirmed by total synthesis. These Alkaloids have antifeedant activities against the pink bollworm, Pectinophora gossypiella.

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