2. Academic Validation
  3. ent-Kaurane and cembrane diterpenoids from Isodon sculponeatus and their cytotoxicity

ent-Kaurane and cembrane diterpenoids from Isodon sculponeatus and their cytotoxicity

  • J Nat Prod. 2009 Oct;72(10):1851-6. doi: 10.1021/np900406c.
Li-Mei Li 1,  Guo-You Li,  Jian-Xin Pu,  Wei-Lie Xiao,  Li-Sheng Ding,  Han-Dong Sun
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 19697926 DOI: 10.1021/np900406c
Abstract

Nine new ent-kauranoids, sculponins D-L (1-9), and 14 known Diterpenoids (10-23) were isolated from the aerial parts of Isodon sculponeatus. The structures of the new Diterpenoids were determined by detailed interpretation of their 1D and 2D NMR spectra and HRESIMS. The isolated compounds were evaluated for their cytotoxic activities against a small panel of human Cancer cell lines.

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