2. Academic Validation
  3. Dibenzocyclooctadiene lignans from Schisandra lancifolia and their anti-human immunodeficiency virus-1 activities

Dibenzocyclooctadiene lignans from Schisandra lancifolia and their anti-human immunodeficiency virus-1 activities

  • Chem Pharm Bull (Tokyo). 2010 May;58(5):734-7. doi: 10.1248/cpb.58.734.
Guang-Yu Yang 1,  Peng Fan,  Rui-Rui Wang,  Jing-Li Cao,  Wei-Lie Xiao,  Liu-Meng Yang,  Jian-Xin Pu,  Yong-Tang Zheng,  Han-Dong Sun
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P. R. China.
PMID: 20460806 DOI: 10.1248/cpb.58.734
Abstract

Three new dibenzocyclooctadiene Lignans, schilancifolignans A-C (1-3), together with thirteen known ones, were isolated from the leaves and stems of Schisandra lancifolia. The structures of 1-3 were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compounds 1-3 were tested for their anti-human immunodeficiency virus-1 activities and showed weak bioactivities.

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