2. Academic Validation
  3. Reactive thermoresponsive copolymer scaffolds

Reactive thermoresponsive copolymer scaffolds

  • Chem Commun (Camb). 2010 Dec 7;46(45):8651-3. doi: 10.1039/c0cc03856c.
Benjamin S Murray 1,  Alexander W Jackson,  Clare S Mahon,  David A Fulton
Affiliations

Affiliation

  • 1 Chemical Nanoscience Laboratory, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, UK.
PMID: 20957257 DOI: 10.1039/c0cc03856c
Abstract

Thermoresponsive copolymer scaffolds containing reactive aldehyde functions were prepared and a selection of organic residues conjugated to these copolymer scaffolds through oxime/hydrazone formation. The conjugation of hydrophobic residues affords copolymers whose lower solution critical temperatures are in most cases higher than that of the parent copolymer scaffold.

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