2. Academic Validation
  3. Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes

Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes

  • Chem Commun (Camb). 2011 Mar 21;47(11):3192-4. doi: 10.1039/c0cc04844e.
Zece Zhu 1,  Chuluo Yang,  Xiang Zhou,  Jingui Qin
Affiliations

Affiliation

  • 1 Department of Chemistry, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, Wuhan University, Wuhan 430072, P. R. China.
PMID: 21270994 DOI: 10.1039/c0cc04844e
Abstract

The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of L-argininamide is simple, rapid and cost-effective.

Figures
Products