2. Academic Validation
  3. Chisomicines A-C, limonoids from Chisocheton ceramicus

Chisomicines A-C, limonoids from Chisocheton ceramicus

  • J Nat Prod. 2011 May 27;74(5):1313-7. doi: 10.1021/np200013g.
Ibrahim A Najmuldeen 1,  A Hamid A Hadi,  Khalijah Awang,  Khalit Mohamad,  Kamal Aziz Ketuly,  Mat Ropi Mukhtar,  Soon-Lim Chong,  Gomathi Chan,  Mohd Azlan Nafiah,  Ng Seik Weng,  Osamu Shirota,  Takahiro Hosoya,  Alfarius E Nugroho,  Hiroshi Morita
Affiliations

Affiliation

  • 1 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
PMID: 21428417 DOI: 10.1021/np200013g
Abstract

Three new limonoids, chisomicines A-C (1-3), have been isolated from the bark of Chisocheton ceramicus. Their structures were determined by 2D NMR, CD spectroscopic methods, and X-ray analysis. Chisomicine A (1) exhibited NO production inhibitory activity in J774.1 cells stimulated by LPS dose-dependently at high cell viability.

Figures