2. Academic Validation
  3. New bioactive macrocyclic diterpenoids from Jatropha multifida

New bioactive macrocyclic diterpenoids from Jatropha multifida

  • Bioorg Med Chem Lett. 2011 Nov 15;21(22):6808-10. doi: 10.1016/j.bmcl.2011.09.032.
Boddu Shashi Kanth 1,  Avula Satya Kumar,  Digambar Balaji Shinde,  Kothapalli Hari Babu,  Tuniki Venugopal Raju,  Chityal Ganesh Kumar,  Pombala Sujitha,  Biswanath Das
Affiliations

Affiliation

  • 1 Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 607, India.
PMID: 21996519 DOI: 10.1016/j.bmcl.2011.09.032
Abstract

Two new macrocyclic Diterpenoids, multifidanol (1) and multifidenol (2) along with several known compounds have been isolated from the stem of Jatropha multifida. The structures of the new compounds were established from the extensive studies of their 1D and 2D NMR spectra. The cytotoxic and antimicrobial activities of these two constituents were examined.

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