2. Academic Validation
  3. Trichothecenes: from simple to complex mycotoxins

Trichothecenes: from simple to complex mycotoxins

  • Toxins (Basel). 2011 Jul;3(7):802-14. doi: 10.3390/toxins3070802.
Susan P McCormick 1,  April M Stanley,  Nicholas A Stover,  Nancy J Alexander
Affiliations

Affiliation

  • 1 Bacterial Foodborne Pathogens and Mycology, National Center for Agricultural Utilization Research, U.S. Department of Agriculture-Agriculture Research Service, Peoria, IL 61604, USA. Susan.McCormick@ars.usda.gov
PMID: 22069741 DOI: 10.3390/toxins3070802
Abstract

As the world's population grows, access to a safe food supply will continue to be a global priority. In recent years, the world has experienced an increase in mycotoxin contamination of grains due to climatic and agronomic changes that encourage Fungal growth during cultivation. A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.

Keywords

Type A; Type B; d-type; macrocyclic; mycotoxins; t-type; toxin biosynthesis; trichothecenes.

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