2. Academic Validation
  3. Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases

Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases

  • Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1631-4. doi: 10.1002/anie.201107833.
Esther C Y Woon 1,  Anthony Tumber,  Akane Kawamura,  Lars Hillringhaus,  Wei Ge,  Nathan R Rose,  Jerome H Y Ma,  Mun Chiang Chan,  Louise J Walport,  Ka Hing Che,  Stanley S Ng,  Brian D Marsden,  Udo Oppermann,  Michael A McDonough,  Christopher J Schofield
Affiliations

Affiliation

  • 1 Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
PMID: 22241642 DOI: 10.1002/anie.201107833
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