2. Academic Validation
  3. Secondary metabolites by chemical screening: II. Amycins A and B two novel niphimycin analogs isolated from a high producer strain of elaiophylin and nigericin

Secondary metabolites by chemical screening: II. Amycins A and B two novel niphimycin analogs isolated from a high producer strain of elaiophylin and nigericin

  • J Antibiot (Tokyo). 1990 Jun;43(6):639-47. doi: 10.7164/antibiotics.43.639.
S Grabley 1,  P Hammann,  W Raether,  J Wink,  A Zeeck
Affiliations

Affiliation

  • 1 Hoechst Aktiengesellschaft, Frankfurt a.M., FRG.
PMID: 2257019 DOI: 10.7164/antibiotics.43.639
Abstract

Two novel natural niphimycin analogs, amycins A (5) and B (3) were isolated from the culture broth of the Streptomyces sp. DSM 3816 by chemical screening methods. In addition this strain produces the Antibiotics niphimycin (4), elaiophylin (2) and nigericin (1). Fermentation, isolation, structure elucidation and biological activity of the amycins are described.

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