2. Academic Validation
  3. Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea

Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea

  • Bioorg Med Chem Lett. 2012 Jul 15;22(14):4900-6. doi: 10.1016/j.bmcl.2012.04.133.
T Srikanth Reddy 1,  N Suryakiran,  M Narasimhulu,  D Ramesh,  K Chinni Mahesh,  A Sai Krishna,  P Kavitha,  J Venkateswara Rao,  Y Venkateswarlu
Affiliations

Affiliation

  • 1 Natural Products Chemistry Division, Natural Products Laboratory, Indian Institute of Chemical Technology, Hyderabad 500 007, India.
PMID: 22704923 DOI: 10.1016/j.bmcl.2012.04.133
Abstract

The Sponge Dysidea herbacea was collected from the Mandapam Coast, Tamilnadu, India. Isolated gram quantities of hydroxylated polybrominated diphenyl ether (HO-PBDE) and semi-synthesized a series of new PBDEs derivatives and tested them for Antibacterial and cytotoxic activities.

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