2. Academic Validation
  3. Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume

Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume

  • J Nat Med. 2013 Oct;67(4):799-806. doi: 10.1007/s11418-013-0750-7.
Seikou Nakamura 1,  Katsuyoshi Fujimoto,  Takahiro Matsumoto,  Tomoe Ohta,  Keiko Ogawa,  Haruka Tamura,  Hisashi Matsuda,  Masayuki Yoshikawa
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412, Japan.
PMID: 23456234 DOI: 10.1007/s11418-013-0750-7
Abstract

Five new acylated sucroses, mumeoses K-O, and a new acylated flavonol glycoside, mumeflavonoside A, were isolated from the flower buds of Prunus mume, cultivated in Zhejiang province, China. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effects of the isolated acylated sucroses and flavonol glycosides on Aldose Reductase were also investigated. Several flavonol glycosides including mumeflavonoside A were shown to inhibit Aldose Reductase.

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