2. Academic Validation
  3. Two new labdane diterpenes from fresh leaves of Leonurus japonicus and their degradation during drying

Two new labdane diterpenes from fresh leaves of Leonurus japonicus and their degradation during drying

  • Chem Pharm Bull (Tokyo). 2013;61(5):497-503. doi: 10.1248/cpb.c12-00670.
Hiroyuki Fuchino 1,  Akihiro Daikonya,  Takeo Kumagai,  Yukihiro Goda,  Yutaka Takahashi,  Nobuo Kawahara
Affiliations

Affiliation

  • 1 Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, 1-2 Hachimandai, Tsukuba, Ibaraki 305-0843, Japan. fuchino@nibio.go.jp
PMID: 23649192 DOI: 10.1248/cpb.c12-00670
Abstract

Degradation of the components of Leonurus Herb was examined during drying. Compounds 1 and 2 were detected on TLC at lower temperature, but not at higher temperature. Their chemical structures were determined by spectral methods. They immediately decomposed even at 40°C in chloroform solution. They are believed to be transformed through a retro-aldol reaction. Compounds 1 and 2 have not been previously reported.

Figures
Products